Effects of Intravenous Administration of Human Umbilical Cord Blood Stem Cells in 3-Acetylpyridine-Lesioned Rats

<table>HuUCBMCs grafts partially prevent 3-AP-induced neuronal loss in the brain stem. (a) and (b) show the detection by western blot of calbindin (a) and neuronal nuclei (b, NeuN) in the cerebellum and brain stem of 3-AP-lesioned rats receiving vehicle (3-AP + vehicle rats, white bars) or HuUCBMCs grafts (3-AP + cells rats, black bars). (a1) and (a2) Show representative blots for calbindin, and (b1) and (b2) for NeuN in the cerebellum (a1, b1) and brain stem (a2, b2). Lane 1: naïve rats (control); lane 2: 3-AP + vehicle; lane 3: 3-AP + cells. Results represent the mean ± SEM of 6 to 9 individual animals. <svg height="14.425" id="M44" style="vertical-align:-0.546pt" version="1.1" viewbox="0 0 66.324997 14.425" width="66.324997" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus naïve rats, <svg height="14.8" id="M46" style="vertical-align:-0.546pt" version="1.1" viewbox="0 0 66.324997 14.8" width="66.324997" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus 3-AP + vehicle rats.</table>

Stem Cells International

fig4

Figure 4

Figure 4: Effects of Intravenous Administration of Human Umbilical Cord Blood Stem Cells in 3-Acetylpyridine-Lesioned Rats 