Endothelial Progenitors as Tools to Study Vascular Disease

Figure 1

Strategies for the use of EPCs in vascular disease modelling. A specific EPC cell subtype called OEC can be isolated from human peripheral blood of both healthy donors and patients. In the forward approach, “disease-free” OECs are exposed to disease-relevant conditions or genetic modifications, while in the reverse approach “disease-specific” OECs are studied in comparison to “disease-free” OECs.