Research Article

Comparative Evaluation of Human Mesenchymal Stem Cells of Fetal (Wharton's Jelly) and Adult (Adipose Tissue) Origin during Prolonged In Vitro Expansion: Considerations for Cytotherapy

Figure 1

Proliferation kinetics of WJSC and ADSC over extended in vitro propagation. (a) Number of cumulative population doublings (PD) as a function of time in culture; (b) cell population doubling times—PDT—(hrs) at respective passages; (c) proliferation index (PI; ratio of PD over respective PDT); (d) growth curve of WJSC and ADSC within a single passage (3 to 4). The * and # symbols highlight the points when confluence was reached for WJSC and ADSC, respectively. Dashed and long dashed horizontal lines denote mean values for ADSC and WJSC, respectively.