Detection of the Hematopoietic Stem and Progenitor Cell Marker CD133 during Angiogenesis in Three-Dimensional Collagen Gel Culture
Figure 7
Immunoelectron microscopy of CD133. (a) At the bottom side of the collagen gels, CD133-positive cells made contact with each other (arrows). Cell organelles were sparse in the cells. Scale bar = 5 μm. (b) CD133-negative cells made contact with each other in the middle layer of the collagen gels (). Scale bar = 5 μm. (c) Enlargement of (b) (). These cells formed intercellular vacuolar structures (arrow). Cell organelles, such as the rough endoplasmic reticulum, were rich in these cells. Scale bar = 1 μm.