Impact of Lipid Nutrition on Neural Stem/Progenitor Cells

Figure 2

Neocortical development in the mouse. Preplate (PP) is composed of the earliest born neurons, which are differentiated from NSPCs in the VZ. PP is split into the subplate (SP) and marginal zone (MZ). NSPCs in the VZ also produce basal progenitor cells, resulting in the formation of the SVZ. The SP and MZ will form a part of layer 6 and the whole of layer 1 of the neocortex, respectively. Later, newborn neurons that form the cortical plate (CP) will form the multilayered neocortex in the postnatal brain, between layer 1 and layer 6. RG cells: radial glial cells, IZ: intermediate zone, and MW: white matter.