Contribution of Mouse Embryonic Stem Cells and Induced Pluripotent Stem Cells to Chimeras through Injection and Coculture of Embryos

Table 3

Generation of chimeric mice using iPSCs.

Method	Number of embryos transferred	Number of recipients	Number of pregnant recipients; (%)	Number of pups	Number of chimeras; (%)
8-cell coculture	341	16	1 (6.3)^a	1	0 (0)
8-cell injection	192	11	10 (90.9)^b	58	8 (13.8)^a
Blastocyst injection	287	14	9 (64.3)^b	83	0 (0)^b
Total	820	41	20 (48.8)	142	8 (5.6)

Values with different superscripts within the same column are significantly different ().