Contribution of Mouse Embryonic Stem Cells and Induced Pluripotent Stem Cells to Chimeras through Injection and Coculture of Embryos

Table 4

Germline-transmitting chimeras produced from ESCs.

Method	Germline transmission
	Tested	Fertile (%)	Germline (%)
8-cell coculture	14	11 (78.6)^a	5 (45.5)^ab
8-cell injection	15	13 (86.7)^a	9 (69.2)^a
Blastocyst injection	13	12 (92.3)^a	1 (8.3)^b
Total	42	36 (85.7)^a	15 (75.0)

Values with different superscripts within the same column are significantly different ().