Whole Genome Expression Profiling and Signal Pathway Screening of MSCs in Ankylosing Spondylitis

Table 2

GO analysis of ankylosing spondylitis with different biological processes related to gene.

Category	GO ID	Term	Count of genes	Percent of count of genes	Fold enrichment	value
GOTERM_BP	GO:0002376	Immune system process	50	12.69	1.7	0.00016
GOTERM_BP	GO:0002520	Immune system development	19	4.82	2.03	0.00285
GOTERM_BP	GO:0003006	Reproductive developmental process	14	3.55	2.05	0.00898
GOTERM_BP	GO:0006325	Chromatin organization	21	5.33	1.95	0.00276
GOTERM_BP	GO:0006816	Calcium ion transport	13	3.3	2.71	0.00107
GOTERM_BP	GO:0006950	Response to stress	64	16.24	1.35	0.00765
GOTERM_BP	GO:0006996	Organelle organization	54	13.71	1.4	0.00669
GOTERM_BP	GO:0007154	Cell communication	71	18.02	1.59	0.00005
GOTERM_BP	GO:0007165	Signal transduction	108	27.41	1.24	0.00756
GOTERM_BP	GO:0007242	Intracellular signaling cascade	73	18.53	1.7	0
GOTERM_BP	GO:0007243	Protein kinase cascade	25	6.35	1.71	0.00663
GOTERM_BP	GO:0007275	Multicellular organismal development	100	25.38	1.28	0.00422
GOTERM_BP	GO:0009891	Positive regulation of biosynthetic process	37	9.39	2.02	0.00004
GOTERM_BP	GO:0009893	Positive regulation of metabolic process	46	11.68	1.87	0.00003
GOTERM_BP	GO:0009966	Regulation of signal transduction	46	11.68	1.85	0.00004
GOTERM_BP	GO:0009967	Positive regulation of signal transduction	20	5.08	2.32	0.00044
GOTERM_BP	GO:0010212	Response to ionizing radiation	6	1.52	3.8	0.0048
GOTERM_BP	GO:0010557	Positive regulation of macromolecule biosynthetic process	34	8.63	1.98	0.00011
GOTERM_BP	GO:0010604	Positive regulation of macromolecule metabolic process	44	11.17	1.92	0.00002
GOTERM_BP	GO:0010627	Regulation of protein kinase cascade	15	3.81	2.07	0.00632
GOTERM_BP	GO:0010628	Positive regulation of gene expression	32	8.12	2.11	0.00006
GOTERM_BP	GO:0010646	Regulation of cell communication	50	12.69	1.75	0.00008
GOTERM_BP	GO:0010647	Positive regulation of cell communication	21	5.33	2.25	0.00048
GOTERM_BP	GO:0010740	Positive regulation of protein kinase cascade	13	3.3	2.55	0.00185
GOTERM_BP	GO:0015674	Di-, trivalent inorganic cation transport	13	3.3	2.27	0.00501
GOTERM_BP	GO:0016568	Chromatin modification	18	4.57	2.26	0.00114
GOTERM_BP	GO:0018108	Peptidyl-tyrosine phosphorylation	9	2.28	3.21	0.00197
GOTERM_BP	GO:0018212	Peptidyl-tyrosine modification	9	2.28	3.15	0.00225

Part of GO analysis of biological processes is supplied here; more data can be found in additional files.