Review Article
MicroRNA Regulation of Brain Tumour Initiating Cells in Central Nervous System Tumours
Table 2
miRNAs regulating BTICs in MB.
| MicroRNAs | Targets | Expression in MB/BTICs of MB | Reference |
| miR-124 | CDK6 | Reduced | [110, 111] | SLC16A1 | miR-125b | Shh signaling pathway | Reduced | [108] | miR-324 | Reduced | [108] | miR-326 | Reduced | [108] | miR-193 | Wnt signaling pathway | Reduced | [118] | miR-224 | Reduced | [118] | miR-1280 | JAG2 | Reduced | [120] | miR-218 | CDK6, RICTOR, CTSB | Reduced | [112] | miR-199b | HES1 | Reduced | [113] | miR-34a | c-MET, Notch-1, Notch-2, CDK6, MAGE-A, DLL2 | Reduced | [68, 116, 117] | miR-9 | t-TrkC | Reduced | [109] | miR-125 | Reduced | [109] | miR-128a/b | Bmi1 | Reduced | [109] | miR-135a | Arhgef6 | Reduced | [121] | miR-21 | PDCD4 | Increased | [124, 127] | miR-182/96/183 | Wnt signaling pathway | Increased | [124] | miR-17/92 | PTEN, Shh pathway | Increased | [109, 122, 123] | miR-142 | GATA1, TAL1/E47 | Increased | [125] | miR-30b/30d | Undefined | Increased | [128] |
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