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Stem Cells International
Volume 2015, Article ID 150609, 10 pages
http://dx.doi.org/10.1155/2015/150609
Review Article

Umbilical Cord Tissue-Derived Cells as Therapeutic Agents

1National Taras Shevchenko University of Kyiv, Kyiv, Ukraine
2Hemafund Ltd., Lisozakhysna Street 5, Kyiv, Ukraine
3International Clinical Research Center, St. Anne’s University Hospital and Masaryk University, Pekarska 53, 656 91 Brno, Czech Republic

Received 31 August 2014; Accepted 21 November 2014

Academic Editor: Pritha Ray

Copyright © 2015 Olga Maslova et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Although the characteristics of SC, including UC-derived cells, are a dramatically discussed issue, this review will focus particularly on some controversial issues regarding clinical utility of cells isolated from UC tissue. UC-derived cells have several advantages compared to other types and sources of stem cells. The impact of UC topography on cell characteristics is briefly discussed. The necessity to adapt existing methods of cell isolation and culturing to GMP conditions is mentioned, as well as possible cryopreservation of this material. Light is shed on some future perspectives for UC-derived cells.