Research Article

Bcl-xL Genetic Modification Enhanced the Therapeutic Efficacy of Mesenchymal Stem Cell Transplantation in the Treatment of Heart Infarction

Table 1

Echocardiography at 4 weeks after MSC transplantation.

GroupLVDd (mm)LVDs (mm)LVEF (%)LVFS (%)

Sham4.57 ± 0.032.34 ± 0.0482.95 ± 0.9548.80 ± 0.10
Medium6.87 ± 0.035.06 ± 0.0744.79 ± 0.2526.35 ± 0.35
Vector-MSC6.66 ± 0.044.81 ± 0.0347.22 ± 0.0927.78 ± 0.39
hBcl-xL-MSC5.99 ± 0.013.89 ± 0.0459.60 ± 0.3035.06 ± 0.11

Differences of statistical significance versus medium group, = 6, .
Differences of statistical significance versus vector-MSC group, = 6, .