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Stem Cells International
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Stem Cells International
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2015
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Article
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Tab 1
/
Research Article
Osteopontin Overexpression Induced Tumor Progression and Chemoresistance to Oxaliplatin through Induction of Stem-Like Properties in Human Colorectal Cancer
Table 1
Clinicopathological correlation of OPN overexpression in CRC (
).
Clinicopathological features
Category
Number of cases
OPN overexpression
(ΔΔCt) (mean ± SEM)
value
Age
<65
65
34
50
−0.613 ± 0.475
−0.767 ± 0.371
0.798
Gender
Male
Female
59
25
−0.542 ± 0.335
−1.089 ± 0.581
0.394
Tumor size
<5 cm
5 cm
49
35
−0.824 ± 0.412
−0.537 ± 0.400
0.630
Histological grade
Well/moderate
Poor/undifferentiated
75
9
0.599 ± 0.309
−3.024 ± 1.472
0.020
Lymph node metastasis
Absent
Present
37
47
−0.081 ± 0.422
−1.196 ± 0.390
0.057
Tumor AJCC stage
I to II
III to IV
31
53
0.219 ± 0.474
−1.245 ± 0.352
0.014
Distant metastasis
Absent
Present
64
20
−0.427 ± 0.338
−1.594 ± 0.537
0.088