A 3D Porous Gelatin-Alginate-Based-IPN Acts as an Efficient Promoter of Chondrogenesis from Human Adipose-Derived Stem Cells

Figure 7

Gene expression profiles of (a) Sox9 ( (hADSCs/G-A-PAA versus hADSCs/G-A bioconstruct: 3 days); (hADSCs/G-A-PAA versus hADSCs/G-A bioconstruct: 7 days and 14 days); ^••• (hADSCs/G-A: 7 days versus 3 days and 28 days versus 14 days); ^### (hADSCs/G-A-PAA: 7 days versus 3 days and 28 days versus 14 days)), (b) Col2a1 ( (hADSCs/G-A-PAA versus hADSCs/G-A bioconstruct: 7 days); (hADSCs/G-A-PAA versus hADSCs/G-A bioconstruct: 14 days and 28 days); ^••• (hADSCs/G-A: 7 days versus 3 days); ^# (hADSCs/G-A-PAA: 3 days versus T0); ^### (hADSCs/G-A-PAA: 7 days versus 3 days)), (c) CEP68 ( (hADSCs/G-A-PAA versus hADSCs/G-A bioconstruct: 7 days); (hADSCs/G-A-PAA versus hADSCs/G-A bioconstruct: 14 days and 28 days); ^•• (hADSCs/G-A: 7 days versus 3 days); ^### (hADSCs/G-A-PAA: 7 days versus 3 days)), (d) COMP ( (hADSCs/G-A-PAA versus hADSCs/G-A bioconstruct: 7 days); (hADSCs/G-A-PAA versus hADSCs/G-A bioconstruct: 28 days); (hADSCs/G-A-PAA versus hADSCs/G-A bioconstruct: 14 days); ^••• (hADSCs/G-A: 28 days versus 14 days); ^## (hADSCs/G-A-PAA: 28 days versus 14 days)) as revealed by qPCR analysis and GraphPad Prism 3.0 data statistical analysis.

(a)

(b)

(c)

(d)