Research Article

Peripheral Blood Derived Mononuclear Cells Enhance the Migration and Chondrogenic Differentiation of Multipotent Mesenchymal Stromal Cells

Figure 3

Change in mRNA levels after 24 h PBMC stimulation with a cut-off value of 4. (a) A scatter plot showing up- and downregulated genes and core genes with no change (). (b) A heat map visualization of 2log2-fold change of the 84 genes in the stem cell PCR array (red: upregulated and green: downregulated). Grey shows the genes that were undetermined (no Ct value with a cut-off value of 35). (c) Real-time PCR validation of 5 key chondrogenic genes () normalized to B2M housekeeping gene mRNA levels.