Research Article
WNT/β-Catenin Signaling Is Required for Integration of CD24+ Renal Progenitor Cells into Glycerol-Damaged Adult Renal Tubules
Figure 1
Endogenous β-catenin/TCF reporter transgene activity following glycerol-induced renal tubular injury in adult mice. (a and b) No β-galactosidase signal is seen in uninjured or glycerol-treated mouse kidneys of CD1 wild-type mice. (c) β-galactosidase signaling is minimal in the uninjured β-catenin/TCF reporter mouse kidney. (d–f) Strong β-catenin/TCF reporter activity (X-Gal, blue) is seen in renal tubules of adult mouse kidney 3 days after glycerol-induced renal injury. Scale bars: 50 μm.
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