Research Article

WNT/β-Catenin Signaling Is Required for Integration of CD24+ Renal Progenitor Cells into Glycerol-Damaged Adult Renal Tubules

Table 1

Wnt mRNA expression in mouse embryonic and adult kidney.

Wnt4Wnt7bWnt9bWnt11

E15 mouse kidney++++
CD24+ cells (E15)++No+
Adult kidney (no glycerol) No++No
Adult kidney (with glycerol)+++No

Transcripts for each Wnt were identified by RT/PCR in E15 mouse kidney, CD24 cells isolated by FACS from E15 mouse kidney, normal adult mouse kidney, and adult mouse kidney 3 days after induction of glycerol-induced proximal tubular injury.