Electrospun Gelatin/-TCP Composite Nanofibers Enhance Osteogenic Differentiation of BMSCs and In Vivo Bone Formation by Activating Ca²⁺-Sensing Receptor Signaling

Figure 8

Histological analysis of bone formation at ((a)–(d)) 4 weeks and ((e)–(h)) 12 weeks after implantation. ((a), (b), (e), and (f)) H&E staining; ((c), (d), (g), and (h)) Masson’s trichrome staining; ((a), (c), (e), and (g)) gelatin group; ((b), (d), (f), and (h)) gelatin/β-TCP group. Black arrows denote the regularly patterned fibrous tissues. (HB: host bone; NB: nascent bone; V: vessels; FT: fibrous tissue). Scale bar = 800 µm (low magnification) and 75 µm (high magnification).

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