Review Article

Trophic Factors from Tissue Stem Cells for Renal Regeneration

Table 1

The summary of trophic effect of secreted factors from tissue stem cells.

AuthorCell line nameSpeciesLocation

Hishikawa et al. [61] SP cellsMouseRenal interstitial space
Challen et al. [62] SP cellsMouseProximal tubules
Inowa et al. [30]SP cellsHumanNot identified
Dekel et al. [33]Sca1+ cellsMouseNontubular
Gupta et al. [34]MRPCsRatRenal tubules
Maeshima et al. [4, 35]LRC cellsRatRenal tubular cells
Oliver et al. [63] Slow-cycling cellsMouse, ratRenal papilla
Bussolati et al. [36, 39]CD133+ CD24+ cellsHumanBowman’s capsule, inner medullary papilla, S3 segment of proximal tubules, interstitium
Sallustio et al. [37, 38]CD133+ CD24+ cellsHumanTubules, glomerulus
Sagrinati et al. [64] CD133+ CD24+ cellsHumanBowman’s capsule
Lindgren et al. [65] CD133+ CD24+ cellsHumanRenal proximal tubules
Kitamura et al. [41]KS cellsRatS3 segment of proximal tubules

SP cells: Side population cells, MRPC cells: Multipotent renal progenitor cells, LRCs: Label-retaining cells, KS cells: kidney stem/progenitor cells.