Review Article

Concise Review: Are Stimulated Somatic Cells Truly Reprogrammed into an ES/iPS-Like Pluripotent State? Better Understanding by Ischemia-Induced Multipotent Stem Cells in a Mouse Model of Cerebral Infarction

Figure 2

Evidence that iSCs lacking Oct4 have different traits compared with those of ES/iPS cells, suggesting that somatic cells in adult mouse brains have limited reprogramming potential in response to stimuli.