Stem Cells International / 2015 / Article / Tab 2 / Research Article
Dynamic Network-Based Relevance Score Reveals Essential Proteins and Functional Modules in Directed Differentiation Table 2 (a) The ten functions highest in relevance score from the LSB to LSB/S/F8 condition. (b) The ten functions highest in relevance score from the LSB/S/F8 to LSB/S/F8/CHIR condition.
(a) Rank LSB → LSB/S/F8 Relevance score Function P value of ontology analysis1 7.627697307 Huntington disease 2 5.389941296 Integrin signaling pathway 3 4.865942264 Gonadotropin releasing hormone receptor pathway 4 4.776453757 Angiogenesis 5 3.318549657 PDGF signaling pathway 6 3.13212684 Cytoskeletal regulation by Rho GTPase 7 3.120593534 FGF signaling pathway 8 3.016342937 EGF receptor signaling pathway 9 2.417680991 TGF-beta signaling pathway 10 2.36486466 Parkinson disease
(b) Rank LSB/S/F8 → LSB/S/F8/CHIR Relevance score Function P value of ontology analysis1 7.085580216 Gonadotropin releasing hormone receptor pathway 2 6.595569241 Integrin signaling pathway 3 4.956190934 FGF signaling pathway 4 4.634381934 Angiogenesis 5 4.535296087 EGF receptor signaling pathway 6 3.702903524 Huntington disease 7 3.299706184 PDGF signaling pathway 8 2.664383051 Parkinson disease 9 2.640768983 TGF-beta signaling pathway 10 2.61175047
RAS pathway