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Stem Cells International
Volume 2015, Article ID 796215, 11 pages
http://dx.doi.org/10.1155/2015/796215
Research Article

Human Mesenchymal Stromal Cells Transplantation May Enhance or Inhibit 4T1 Murine Breast Adenocarcinoma through Different Approaches

1Human Genome and Stem-Cell Center (HUG-CELL), Institute of Bioscience, University of São Paulo, 05508-090 São Paulo, SP, Brazil
2Laboratory of Cancer Immunobiology, Department of Microbiology, Immunology and Parasitology, Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP), 04023-062 São Paulo, SP, Brazil
3Stomatology Department, Faculty of Dentistry, University of São Paulo, 05508-000 São Paulo, SP, Brazil

Received 26 December 2014; Revised 9 March 2015; Accepted 10 March 2015

Academic Editor: Luca Magnani

Copyright © 2015 T. Jazedje et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [9 citations]

The following is the list of published articles that have cited the current article.

  • Adam Nowakowski, Katarzyna Drela, Justyna Rozycka, Miroslaw Janowski, and Barbara Lukomska, “Engineered Mesenchymal Stem Cells as an Anti-Cancer Trojan Horse,” Stem Cells and Development, 2016. View at Publisher · View at Google Scholar
  • Yanhui Cai, Yujing Xi, Zhongyuan Cao, Geng Xiang, Qingrong Ni, Rui Zhang, Jing Chang, Xiao Du, Angang Yang, Bo Yan, and Jing Zhao, “Dual targeting and enhanced cytotoxicity to HER2-overexpressing tumors by immunoapoptotin-armored mesenchymal stem cells,” Cancer Letters, 2016. View at Publisher · View at Google Scholar
  • Ningning He, Yang Li, Yang Xu, Xiaoyan Xie, Hui Wang, Xuetao Pei, Na Liu, Zongjin Li, Guowei Feng, Yuebing Wang, and Lailiang Ou, “Embryonic stem cell preconditioned microenvironment suppresses tumorigenic properties in breast cancer,” Stem Cell Research and Therapy, vol. 7, no. 1, 2016. View at Publisher · View at Google Scholar
  • Amanda Assoni, Giuliana Coatti, Marcos C. Valadares, Melinda Beccari, Juliana Gomes, Mayra Pelatti, Miguel Mitne-Neto, Valdemir M. Carvalho, and Mayana Zatz, “Different Donors Mesenchymal Stromal Cells Secretomes Reveal Heterogeneous Profile of Relevance for Therapeutic Use,” Stem Cells and Development, 2016. View at Publisher · View at Google Scholar
  • Kevin Dzobo, Matjaz Vogelsang, Nicholas E. Thomford, Collet Dandara, Karlien Kallmeyer, Michael S. Pepper, and M. Iqbal Parker, “ Wharton’s Jelly-Derived Mesenchymal Stromal Cells and Fibroblast-Derived Extracellular Matrix Synergistically Activate Apoptosis in a p21-Dependent Mechanism in WHCO1 and MDA MB 231 Cancer Cells In Vitro ,” Stem Cells International, vol. 2016, pp. 1–17, 2016. View at Publisher · View at Google Scholar
  • Juliana P. A. Gomes, Amanda F. Assoni, Mayra Pelatti, Giuliana Coatti, Swaldo Keith Okamoto, and Mayana Zatz, “Deepening a simple question: Can MSCs be used to treat cancer?,” Anticancer Research, vol. 37, no. 9, pp. 4747–4758, 2017. View at Publisher · View at Google Scholar
  • Fengqi Yan, Xia Li, Nan Li, Rui Zhang, Qinhao Wang, Yi Ru, Xiaoke Hao, Jianxin Ni, He Wang, and Guojun Wu, “Immunoproapoptotic molecule scFv-Fdt-tBid modified mesenchymal stem cells for prostate cancer dual-targeted therapy,” Cancer Letters, 2017. View at Publisher · View at Google Scholar
  • Simone Pacioni, Quintino Giorgio D’Alessandris, Stefano Giannetti, Liliana Morgante, Valentina Coccè, Arianna Bonomi, Mariachiara Buccarelli, Luisa Pascucci, Giulio Alessandri, Augusto Pessina, Lucia Ricci-Vitiani, Maria Laura Falchetti, and Roberto Pallini, “Human mesenchymal stromal cells inhibit tumor growth in orthotopic glioblastoma xenografts,” Stem Cell Research & Therapy, vol. 8, no. 1, 2017. View at Publisher · View at Google Scholar
  • Marcos Freitas Cordeiro, Luana Patricia Marmitt, and Ana Paula Horn, “Subcutaneous injection of multipotent mesenchymal stromal cells admixed with melanoma cells in mice favors tumor incidence and growth: a systematic review and meta-analysis,” Archives of Dermatological Research, 2018. View at Publisher · View at Google Scholar