Research Article

TGF-β1 Induces the Dual Regulation of Hepatic Progenitor Cells with Both Anti- and Proliver Fibrosis

Figure 1

Transforming growth factor-beta 1 (TGF-β1) induced a mesenchymal morphology in HPCs. HPCs were cultured in the presence (10 ng/mL) or absence of TGF-β1 for 48 h. The phenotypic changes (transition toward a myofibroblast-like phenotype) were evaluated by phase-contrast microscopy and Giemsa staining (a). Changes in differentiation markers were evaluated by western blot (b).
(a)
(b)