TGF-β1 Induces the Dual Regulation of Hepatic Progenitor Cells with Both Anti- and Proliver Fibrosis

Table 2

Variation in the ECM related gene expression between HPCs control and TGF-β1-treated HPCs in RT² profiler PCR array.

Group	Position	Gene bank	Symbol	Description	Upregulation or downregulation
HPC + TGF-β1 (12 h)/HPC	E7	NM_000602	SERPINE1	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	12.8
	C6	NM_002205	ITGA5	Integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	−4.7
HPC + TGF-β1 (48 h)/HPC	A10	NM_000089	COL1A2	Collagen, type I, alpha 2	40.0
	D5	NM_004994	MMP9	Matrix metallopeptidase 9 (gelatinase B, 92 kDa gelatinase, 92 kDa type IV collagenase)	13.4
	G8	NM_004626	WNT11	Wingless-type MMTV integration site family, member 11	6.0
	E7	NM_000602	SERPINE1	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	−5.1