Review Article

Emerging Implications for Extracellular Matrix-Based Technologies in Vascularized Composite Allotransplantation

Figure 3

Extracellular matrix-derived biomaterials: Materials derived from the ECM via decellularization of native tissues possess a number of beneficial properties that together promote constructive tissue remodeling. ECM-derived biomaterials can modulate wound healing mechanisms including angiogenesis and the immune system and facilitate important cellular processes such as cell migration, proliferation, and differentiation.