Utility of Lymphoblastoid Cell Lines for Induced Pluripotent Stem Cell Generation

Figure 4

Gene expression patterns in LCLs, reprogrammed iPSC, and ESCs. (a) Expression pattern of all DE mRNAs and miRNAs in LCLs and their reprogrammed iPSCs. (b) Expression profiles of LCL specific mRNAs and miRNAs in LCLs and their reprogrammed iPSCs. (c) Expression profiles of mRNAs and miRNAs known from the literature to be involved in maintenance of pluripotency and stemness in human ESC/iPSCs. (d) PCA on gene expression profiles of six LCLs and their reprogrammed iPSCs generated in this study and three ESC and four iPSC gene expression profiles downloaded from the GEO database.

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