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Stem Cells International
Volume 2016, Article ID 2452985, 8 pages
http://dx.doi.org/10.1155/2016/2452985
Research Article

Modeling Neurological Disease by Rapid Conversion of Human Urine Cells into Functional Neurons

1Department of Neurology, Institute of Neurology, Huashan Hospital, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai 200040, China
2Department of Neurology, Research Center of Neurology in Second Affiliated Hospital, and the Collaborative Innovation Center for Brain Science, Zhejiang University School of Medicine, Hangzhou 310009, China
3Department of Anatomy, Histology & Embryology, Shanghai Medical College, Fudan University, Shanghai 200030, China
4Institutes of Brain Science, Institute of Neurobiology and State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai 200030, China

Received 11 April 2015; Revised 18 July 2015; Accepted 22 July 2015

Academic Editor: Gary E. Lyons

Copyright © 2016 Shu-Zhen Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [9 citations]

The following is the list of published articles that have cited the current article.

  • Ying Chen, Jiali Pu, and Baorong Zhang, “Progress and Challenges of Cell Replacement Therapy for Neurodegenerative Diseases Based on Direct Neural Reprogramming,” Human Gene Therapy, 2016. View at Publisher · View at Google Scholar
  • Robert F. Halliwell, “Electrophysiological properties of neurons derived from human stem cells and iNeurons in vitro,” Neurochemistry International, 2016. View at Publisher · View at Google Scholar
  • Annachiara Pino, Guido Fumagalli, Francesco Bifari, and Ilaria Decimo, “New neurons in adult brain: distribution, molecular mechanisms and therapies,” Biochemical Pharmacology, 2017. View at Publisher · View at Google Scholar
  • Young M. Lee, Bruna L. Zampieri, Jonah J. Scott-McKean, Mark W. Johnson, and Alberto C.S. Costa, “Generation of Integration-Free Induced Pluripotent Stem Cells from Urine-Derived Cells Isolated from Individuals with Down Syndrome,” STEM CELLS Translational Medicine, 2017. View at Publisher · View at Google Scholar
  • Zhimin Xu, Xingkun Chu, Houbo Jiang, Haley Schilling, Shengdi Chen, and Jian Feng, “Induced Dopaminergic Neurons: A New Promise for Parkinson’s Disease,” Redox Biology, 2017. View at Publisher · View at Google Scholar
  • Xiaoli Ji, Min Wang, Fang Chen, and Junmei Zhou, “Urine-Derived Stem Cells: The Present and the Future,” Stem Cells International, vol. 2017, pp. 1–8, 2017. View at Publisher · View at Google Scholar
  • R. Loera-Valencia, A. Piras, M. A. M. Ismail, S. Manchanda, H. Eyjolfsdottir, T. C. Saido, J. Johansson, M. Eriksdotter, B. Winblad, and P. Nilsson, “Targeting Alzheimer's disease with gene and cell therapies,” Journal of Internal Medicine, vol. 284, no. 1, pp. 2–36, 2018. View at Publisher · View at Google Scholar
  • Joel Wellbourne-Wood, and Jean-Yves Chatton, “From Cultured Rodent Neurons to Human Brain Tissue: Model Systems for Pharmacological and Translational Neuroscience,” ACS Chemical Neuroscience, 2018. View at Publisher · View at Google Scholar
  • Layla T. Ghaffari, Alexander Starr, Andrew T. Nelson, and Rita Sattler, “Representing Diversity in the Dish: Using Patient-Derived in Vitro Models to Recreate the Heterogeneity of Neurological Disease,” Frontiers in Neuroscience, vol. 12, 2018. View at Publisher · View at Google Scholar