Semaphorin 3A Shifts Adipose Mesenchymal Stem Cells towards Osteogenic Phenotype and Promotes Bone Regeneration In Vivo

Figure 6

engrafted PLGA scaffold increases bone repair in the calvarial defect model. Bone regeneration of calvarial defects evaluated by HE staining. Control indicates that defects received nothing; , , and indicate that defects implanted with ASC, , and , respectively. Data presented are representative HE staining images from 5 different experiments. Black arrows point to the defect margins, and the lower panels are the magnifications of the insets in each group.