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Stem Cells International
Volume 2016, Article ID 2681925, 8 pages
Review Article

LncRNAs in Stem Cells

School of Life Sciences and CAS Key Laboratory of Brain Function and Disease, University of Science and Technology of China, Hefei, Anhui 230027, China

Received 5 September 2015; Accepted 3 December 2015

Academic Editor: Yujing Li

Copyright © 2016 Shanshan Hu and Ge Shan. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Noncoding RNAs are critical regulatory factors in essentially all forms of life. Stem cells occupy a special position in cell biology and Biomedicine, and emerging results show that multiple ncRNAs play essential roles in stem cells. We discuss some of the known ncRNAs in stem cells such as embryonic stem cells, induced pluripotent stem cells, mesenchymal stem cells, adult stem cells, and cancer stem cells with a focus on long ncRNAs. Roles and functional mechanisms of these lncRNAs are summarized, and insights into current and future studies are presented.