Review Article

MicroRNAs: From Female Fertility, Germ Cells, and Stem Cells to Cancer in Humans

Table 2

MiRNAs and their target genes related to differentiation of hESCs, development of all three germ layers (endoderm, mesoderm, and ectoderm), and cancer.

DevelopmentReferences
EndodermMesodermCardiomyocytesNeural lineageEndothelial cells, angiogenesisCANCER

miR-302a 
(OTX2)
[89]

miR-302/373 
(LEFTY)
[90]

miR-302 
(NR2F2, JMJD1C)
[91]

miR-1,  
miR-499
[92]

miR-126, 
miR-210
[93]

miR-498[95]

let-7,  
miR-9, miR-30, and miR-125
[96]

let-7 family[97]