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| | Title | Type of cells | Treatment | Disease | Stage | Number of subjects | (Estimated) completion date | Endpoints | Results | Clinicaltials.gov identifier |
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| (1) | Periodontal Regeneration of Chronic Periodontal Disease Patients Receiving Stem Cells Injection Therapy | Allogeneic human DPSCs | Local injection at the local periodontal defects | Chronic periodontal disease | Recruiting | 40 | Dec. 2016 | Improvement of baseline alveolar bone volume and clinical parameters, including probing depth (PD), Clinical Attachment Level (CAL), Quigley-Hein plaque Index (QHI), Bleeding on Probing (BoP) | Not reported yet | NCT02523651 |
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| (2) | Use of Mesenchymal Stem Cells for Alveolar Bone Tissue Engineering for Cleft Lip and Palate Patients | SHED (autologous) | Application of MSCs inside a collagen and hydroxyapatite biomaterial (Geistlich Bio-Oss®) into the defect | Alveolar bone TE for cleft lip and palate patients
(secondary alveolar graft after completion of orthodontic treatment) | Unknown | 5 | Mar. 16 | Amount and quality of regenerated bones (CT scans) | In all 5 patients bone formation closing the alveolar cleft was observed after 6 months | NCT01932164 |
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| (3) | Revitalization of Immature Permanent Teeth with Necrotic Pulps Using SHED Cells | SHED (autologous) | Application of scaffold-free SHED-derived pellet | Immature permanent teeth with pulp necrosis | Recruiting | 80 | Jul. 2017 | Pulp status evaluated by dental pulp vitality tester; pulp revascularization examined by laser Doppler flowmeter; and the index of clinical examination Also, the degree of apical closure; the rate of increase in root length; and the change of root canal wall thickness. | Not reported yet | NCT01814436 |
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| (4) | Effect on Allogenic Mesenchymal Stem Cells on Osseointegration of Dental Implants | Allogeneic human DPSCs | The implant is dipped in the stem cell solution for 3 minutes so that the cells adhere to the titanium implant surface before placement at the osteotomy site | Improvement of implant osseointegration | Enrolling by invitation | 10 | Feb. 2017 | Evaluation of primary and secondary stability is measured using Resonance Frequency Analysis (RFA). | Not reported yet | NCT02731586 |
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