Aryl Hydrocarbon Receptor Deficiency in an Exon 3 Deletion Mouse Model Promotes Hematopoietic Stem Cell Proliferation and Impacts Endosteal Niche Cells

Figure 6

AHR-deficient LSK cells have alterations in gene expression related to hematopoiesis and hematopoietic disease. Quantitative real time PCR was used to analyze mRNA expression of genes associated with hematopoiesis and hematopoietic disease in LSK cells. Differential gene expression analysis of the LSK population in (a) young and (b) old mice. Data are mean ± SD, mice/group. significantly different from WT control ().

(a)

(b)