Clinical Efficacy and Meta-Analysis of Stem Cell Therapies for Patients with Brain Ischemia

Table 3

The correlations of NIHSS and clinical variables across studies by subgroup and heterogeneity analysis.

Subgroup	Mean difference (95% CI)	(%)
Patients’ characteristics
Acute stoke	0.93 (−0.65, 2.51)	57
Chronic stroke	2.28 (1.47, 3.09)	6
Cell type
MSC	1.25 (0.35, 2.14)	38
Non-MSC	2.9 (1.75, 4.05)	—
Route of delivery
Intravenous injection	1.0 (−0.18, 2.17)	41
Non-IV	2.38 (0.77, 3.99)	71
Follow-up period
<6 months	1.41 (0.76, 2.06)	0
6 months	2.07 (−1.10, 5.24)	82