p53-Dependent Senescence in Mesenchymal Stem Cells under Chronic Normoxia Is Potentiated by Low-Dose γ-Irradiation

Figure 4

Effects of oxygen levels on telomeric length. Graph shows quantitative genomic PCR telomeric length determination performed with p53wt/wt mMSCs under hypoxic and normoxic conditions and with a pool of newborn mouse skin DNA as calibrator (set to 100 arbitrary units, AU). Fitted lines are exponential regression curves, and the differences are not significant.