Review Article

Adipose-Derived Stem Cells for Tissue Engineering and Regenerative Medicine Applications

Table 5

List of clinical trials using ASCs.

ConditionNumberPhaseStudy designStudy typeReference

Breast reconstruction2Phase 2ASCs enriched fat graftInterventionalNCT01771913
Phase 4Autologous SVFsInterventionalNCT00616135

Lipoatrophy1Phase 1SVF-enriched fat graftInterventionalNCT01828723

Fistula6Phase 1/Phase 2Allogenic ASCsInterventionalNCT01372969;
NCT00999115
Phase 1Autologous ASCsInterventionalNCT00992485
Phase 2Autologous ASCsInterventionalNCT01011244
Phase 3Autologous ASCsInterventionalNCT00475410
ProspectiveAutologous ASCsObservationalNCT01020825

Liver cirrhosis1Autologous ASCsInterventionalNCT01062750

Cardiovascular disease 4Phase 1Autologous SVFsInterventionalNCT00442806; NCT00426868
Phase 2Autologous ASCsInterventionalNCT01449032;
NCT01216995

Peripheral vascular diseases and cardiovascular diseases1Phase 1/Phase 2Autologous SVFsInterventionalNCT01211028

Urinary incontinence1Phase 2Autologous ASCsInterventionalNCT01799694

Localized adverse reaction to administration of drug1Phase 1Allogenic ASCsInterventionalNCT01743222

Osteoarthritis2Phase 1Autologous ASCs InterventionalNCT01585857
Phase 1/Phase 2Autologous ASCsInterventionalNCT01809769

Buerger’s disease1Phase 1/Phase 2Autologous ASCsInterventionalNCT01302015

Brain injury1Phase 1/Phase 2Autologous ASCsInterventionalNCT01649700

Cerebellar ataxia1Phase 1/Phase 2Allogenic ASCsInterventionalNCT01649687

Spinal cord injury2Phase 1Autologous ASCsInterventionalNCT01274975; NCT01624779

Soft tissue mass removal1SVFsInterventionalNCT01399307

Diabetic foot ulcer1Phase 1Allogenic ASCsInterventionalNCT02394886

Limb ischemia2Phase 1/Phase 2Autologous ASCsInterventionalNCT01257776; NCT01663376

Overweight1ProspectiveBone Grafts using ASCs and different scaffoldsObservationalNCT01218945

Rheumatoid arthritis1Phase 1/Phase 2Allogenic ASCsInterventionalNCT01663116

Degenerative arthritis1Phase 1/Phase 2Autologous ASCsInterventionalNCT01300598

Sepsis1Phase 1Allogenic ASCsInterventionalNCT02328612

Romberg’s disease1Phase 2Autologous ASCsInterventionalNCT01309061

Depressed scar1Phase 2/Phase 3 Autologous ASCsInterventionalNCT00992147

Healthy1Phase 1Allogenic ASCsInterventionalNCT01739530

ASCs, adipose-derived stem cells; SVFs, stromal vascular fraction.