Chondrogenic Potency Analyses of Donor-Matched Chondrocytes and Mesenchymal Stem Cells Derived from Bone Marrow, Infrapatellar Fat Pad, and Subcutaneous Fat

Figure 1

The expression of chondrogenic and hypertrophic genes in monolayer cell populations prior to chondrogenesis. ((a)–(f)) Chondrocytes (Ch), bone marrow MSC (BM), fat pad MSC (FP), and subcutaneous fat MSC (SCF). Data shown are the means ± the standard deviation of triplicate runs and 5 donors for each cell population. One-way ANOVA and post hoc Bonferroni tests were used to test for significant differences in gene expression levels between cell types. (g) Pearson’s correlation analysis matrix comparing genes which may be predictive of chondrogenic potential; significant correlations are in bold. Gene expression is expressed relative to the reference genes PPIA and TBP.

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