Research Article

Fibronectin and Cyclic Strain Improve Cardiac Progenitor Cell Regenerative Potential In Vitro

Figure 1

Cell strain. CPCs were seeded on the appropriate matrix for 6 hours. Video microscopy (19 frames per second) captured the motion of beads tethered to CPCs under cyclic 1 Hz strain. (a) Representative distance tracings from CPCs cultured on cECM; programmed strain is reported on graph. (b) Strain magnitude effects on measured strain. One-way ANOVA with Tukey’s multiple comparison test; bars represent mean + SEM; , , and ; –10; 3.5, 7.0: strain magnitude (%), PLL (brown): poly-L-lysine, LN (green): laminin, FN (purple): fibronectin, COL (blue): collagen I, and cECM (red): naturally derived cardiac extracellular matrix.
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