Highly Synchronized Expression of Lineage-Specific Genes during In Vitro Hepatic Differentiation of Human Pluripotent Stem Cell Lines

Figure 15

Bar graph showing the RNA expression levels of the drug transporters (a) SLC10A1 (NTCP), (b) ABCC2 (MRP2), (c) SLCO1B1 (OATP1B1), and (d) ABCB11 (BSEP). The -axis indicates the hPSC lines at days 31 and 34 of the hepatic differentiation. The -axis indicates RQ, where the calibrator’s RQ = 1. The calibrator was an RNA pool of freshly isolated human primary hepatocytes from 5 different donors.

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