Research Article

Leukemia Stem Cell-Released Microvesicles Promote the Survival and Migration of Myeloid Leukemia Cells and These Effects Can Be Inhibited by MicroRNA34a Overexpression

Figure 5

Effects of and on the levels of caspase-3 and Tim-3 protein in AML cells. (a) The activity of caspase-3 in AML cells which was determined by ELISA. (b) The expression of Tim-3 protein in AML cells which was determined by western blot. Data represents mean ± SEM. versus veh; versus . Veh: fresh culture medium; : LMVs generated from miRCtrl transfected LSCs; and : LMVs generated from miR34a mimic transfected LSCs.
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