Mesenchymal Stem Cells Attenuate Cisplatin-Induced Nephrotoxicity in iNOS-Dependent Manner

Figure 5

MSCs attenuate cisplatin-induced acute kidney injury in iNOS-dependent manner. (a) Serum levels of BUN and creatinine. (b) Histological scores. (c) Representative H&E and PAS-stained mouse kidney (magnifications ×200). (d) Serum levels of cytokines. Total numbers of (e) TNF-α-producing CD45+CD11c+ dendritic cells and IL-17-producing CD8+ cytotoxic T cells, (f) IL-10-producing CD45+CD11c+ DCs and CD4+CD25+FoxP3+ T regulatory cells. Values are mean ± SEM; mice/group. , .

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