Stem Cells International

Review Article

Skeletal Muscle Cell Induction from Pluripotent Stem Cells

Table 1

Myogenic induction by overexpression of transgenes.
AuthorsYearJournalsRefsSpeciesCell typesTransgenesTransgene systemsRemarks
Dekel et al.1992New Biol[109]MouseESCMyoDElectroporationEB culture
Rohwedel et al.1995Exp Cell res[110]MouseESCM-TwistTransfectionEB culture
Prelle et al.2000Biochem Biophys Res Commun[111]MouseESCIGF2ElectroporationEB culture
Myer et al.2001Dev Biol[112]MouseESCMyoD, myogeninElectroporationMyogenin−/− EB culture
Sumariwalla et al.2001Genesis[113]MouseESCMyoD, myogenin, MRF4ElectroporationMyogenin−/− EB culture
Caron et al.2005Oncogene[114]MouseESCHMGA2/TTransfectionEB culture
Kamochi2006Transplantation[115]MouseESCIGF2Transfection2D culture
Ozasa et al.2007Biochem Biophys Res Commun[50]MouseESCMyoDTet-Off system2D culture
Darabi et al.2008Nat Med[15]MouseESCPax3Tet-ON system in integrated geneEB culture, PDGFRα(+) Flk-1(−) cell sorting
Craft et al.2008Stem Cells[116]MouseESCPax3, MyoDHerpes simplex virusEB culture
Warren et al.2010Cell Stem Cell[51]HumaniPSCMyoDmRNA transfectionEB culture
Meier-Stiegen et al.2010PLoS One[117]MouseESCNotch-IC-ERTTMX-ERT system, electroporationEB culture
Darabi et al.2011Stem Cells[58]MouseESCPax7Tet-ON system in integrated geneEB culture, bFGF, PDGFRα(+) Flk-1(−) cell sorting
Iacovino et al.2011Stem Cells[118]Mouse, humanESCMyf5Tet-ON system in integrated gene, Tet-ON-lentiviral vectorEB culture
Thoma et al.2012Cell Reprogram[119]MouseESCMyoDTMX-induction system in transfectionEB culture
Goudenege et al.2012Mol Ther[120]HumanESCMyoDAdenoviral vectorEB culture
Rao et al.2012Stem Cell Rev[121]HumanESCMyoDTet-On system in lentiviral vector2D culture
Tedesco et al.2012Sci Transl Med[80]HumaniPSCMyoD-ERTTMX-ERT system, lentiviral vector2D culture, induction of limb-girdle muscular dystrophy 2D, and DMD patient iPSC for mesoangioblast-like cells
Darabi et al.2012Cell Stem Cell[59]HumanESC/iPSCPax7Tet-ON system in lentiviral vectorEB culture, Pax7(+) cell sorting
Tanaka et al.2013PLoS One[52]HumaniPSCMyoDPiggyBac transposon-Tet-ON system2D culture, Miyoshi myopathy patient hiPSC
Albini et al.2013Cell Rep[54]HumanESCMyoD + Baf60cLentiviral vectorMyosphere culture
Abujarour et al.2014Stem Cells Transl Med[53]HumaniPSCMyoDTet-Off system in lentiviral vector2D culture, DMD patient-derived hiPSC
Yasuno et al.2014Biochem Biophys Res Commun[122]HumaniPSCMyoDPiggyBac transposon-Tet-ON systemEB culture, carnitine palmitoyltransferase II deficiency patient hiPSC
Albini et al.2014J Vis Exp[123]HumanESCMyoD + Baf60cLentiviral vectorMyosphere culture
Li et al.2015Stem Cell Reports[57]HumaniPSCMyoDPiggyBac transposon-Tet-ON system2D culture, DMD patient hiPSCs for gene correction by TALEN and CRISPR-Cas9
Maffioletti et al.2015Nat Protoc[124]HumanESC/iPSCMyoD-ERTTMX-ERT system, lentiviral vector2D culture, induction of limb-girdle muscular dystrophy 2D, and DMD patient iPSC for mesoangioblast-like cells
Shoji et al.2015Sci Rep[56]HumaniPSCMyoDPiggyBac transposon-Tet-ON system2D culture, DMD patient hiPSCs for exon skipping
Dixon et al.2016Proc Natl Acad Sci U S A.[125]HumanESCMyoDGAG-binding motif for cell penetrating peptide2D culture
Shoji et al.2016Methods Mol Biol[126]HumaniPSCMyoDPiggyBac transposon-Tet-ON system2D culture
Akiyama et al.2016Development[127]HumaniPSCMyoD + JMJD3PiggyBac transposon-Tet-ON system2D culture
Magli et al.2016Methods Mol Biol[128]MouseESCPax3Tet-ON system in integrated geneEB culture, PDGFRα(+) Flk-1(−) cell sorting