Skeletal Muscle Cell Induction from Pluripotent Stem Cells

Table 2

Myogenic induction without transgenes.

Authors	Year	Refs	Journals	Species	Cell types	Factors	Remarks
Zhuang et al.	1992	[129]	Proc Natl Acad Sci U S A	Mouse	ESC		E2A^−/− EB culture
Dinsmore et al.	1996	[130]	Cell Transplant	Mouse	ESC	RA, DMSO	EB culture of androgenetic and parthenogenetic ESC
Rohwedel et al.	1998	[131]	Exp Cell Res	Mouse	ESC	LiCl	EB culture
Barberi et al.	2005	[82]	PLoS Med	Human	ESC	OP9 and C2C12 coculture	CD73(+) MSC sorting
Barberi et al.	2007	[83]	Nat Med	Human	ESC	OP9 coculture, insulin	CD73(+) MSC sorting, NCAM(+) cell sorting
Sakurai et al.	2008	[85]	Stem Cells	Mouse	ESC		2D culture, PDGFRα(+) Flk-1(−) cell sorting
Sasaki et al.	2008	[132]	Differentiation	Mouse	ESC	Spermine	EB culture
Chang et al.	2009	[86]	FASEB J	Mouse	ESC		EB culture, SM/C-2.6(+) cell sorting
Sakurai et al.	2009	[68]	Stem Cell Res	Mouse	ESC	LiCl, BMP4	2D culture, PDGFRα(+) E-cadherin(low) cell sorting
Mizuno et al.	2010	[87]	FASEB J	Mouse	iPSC		EB culture, SM/C-2.6(+) cell sorting
Teng et al.	2010	[133]	J Cell Biochem	Human	ESC	TGFβ inhibitor	GNE^−/− EB culture
Awaya et al.	2012	[134]	PLoS One	Human	ESC/iPSC		EB culture
Sakurai et al.	2012	[135]	PLoS One	Mouse, human	ESC	LiCl, BMP4, Activin A	2D culture
Kuraitis et al.	2012	[136]	Eur Cell Mater	Mouse	ESC	sLeX-collagen matrices	EB culture
Xu et al.	2013	[70]	Cell	Human	iPSC	GSK3β inhibitor, bFGF, forskolin	EB culture
Leung et al.	2013	[137]	Biomacromolecules	Human	ESC	Chitosan-polycaprolactone (C-PCL) nanofibers + Wnt3a	2D culture
Borchin et al.	2013	[72]	Stem Cell Reports	Human	iPSC	GSK3β inhibitor	2D culture, c-met(+) cell sorting
Hosoyama et al.	2013	[75]	Stem Cells Transl Med	Human	ESC/iPSC	bFGF, EGF	EZ sphere culture
Hwang et al.	2014	[69]	Sci Rep	Mouse	ESC	Wnt3a	2D culture, PDGFRα(+) cell sorting
Shelton et al.	2014	[73]	Cell Reports	Mouse, human	ESC/iPSC	GSK3β inhibitor, BMP, VEGF, Inhibinβ, bFGF	EB culture
Chal et al.	2015	[76]	Nat Biotechnol	Mouse, human	ESC/iPSC	GSK3β inhibitor, BMP inhibitor	2D culture
Chal et al.	2016	[77]	Nat Protoc	Human	iPSC	GSK3β inhibitor, BMP inhibitor, bFGF, HGF, IGF1	2D culture
Caron et al.	2016	[74]	Stem Cell Transl Med	Human	ESC	GSK3β inhibitor, Ascorbic acid, Alk5 inhibitor, Dex, EGF, insulin	2D culture