An Overview of Lipid Droplets in Cancer and Cancer Stem Cells

Figure 5

Hypothetical model of NF-kB/SCD1 pathway based on [177, 185]. Activated NF-kB pathway stimulates SCD1 upregulation, which could modulate several pathways (such as Wnt/β-catenin and YAP/TAZ signalings) resulting in CSC proliferation, cancer invasiveness, and tumorigenesis.