A Concise Review on the Use of Mesenchymal Stem Cells in Cell Sheet-Based Tissue Engineering with Special Emphasis on Bone Tissue Regeneration

Figure 4

The gross (a) and microscopic (b) appearances of osteotomy site in the osteogenic-sheet group at the end of the second week. Callus formation was observed in the osteogenic-sheet group at the osteotomy site at the end of the second week (a). In microscopic examination, the osteogenic-sheet group exhibited a mainly cartilaginous (arrows) but also at some locations bony elements (arrow heads) containing callus formation at the end of the second week (b). Scale bar = 1 mm for (b).

(a)

(b)