Pulsed Electromagnetic Field Regulates MicroRNA 21 Expression to Activate TGF-β Signaling in Human Bone Marrow Stromal Cells to Enhance Osteoblast Differentiation

Table 5

Real-time RT-PCR of three different female donor samples’ hBMSCs, aged 24, 27, and 31 years in the differentiation stage. Analysis by Student’s t-test.

Gene symbol	Gene title	Average PEMF/control %	p
COL1A1	Collagen, type I, alpha 1	133 ± 24%
COL5A1	Collagen, type V, alpha 1	136 ± 25%
CTNNA1	Catenin (cadherin-associated protein), alpha 1, 102 kDa	124 ± 3%
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	127 ± 33%
SOX11	SRY- (sex determining region Y-) box 11	138 ± 24%
SPP1	Secreted phosphoprotein 1	131 ± 41%
TGFB2	Transforming growth factor, beta 2	155 ± 44%
TBRG1	Transforming growth factor beta regulator 1	143 ± 23%
AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	74 ± 15%
FBN2	Fibrillin 2	35 ± 14%
IL8	Interleukin 8	56 ± 35%