Application of the AMLprofiler Diagnostic Microarray in the South African Setting

Table 1

Chromosomal aberrations and molecular marker variants detected by AMLprofiler.

Markers on AMLprofiler		Prognostic category
Chromosomal aberrations	inv(16)(p13q22)/t(16;16)(p13;q22)	Favorable
	t(8;21)(q22;q22)	Favorable
	t(15;17)(q24;q21)	Favorable
Gene mutations	CEBPA double mutant	Favorable
	NPM1-ABD mutations	Favorable
Gene expression	EVI1-high expression	Unfavorable
	BAALC-low expression	Favorable