Galectin-3 Knockdown Impairs Survival, Migration, and Immunomodulatory Actions of Mesenchymal Stromal Cells in a Mouse Model of Chagas Disease Cardiomyopathy

Figure 6

Modulation of collagen synthesis in the heart after administration of MSC. Representative images of Sirius red stained heart sections of T. cruzi infected mice administered with saline (a), MSC-WT (b), or MSC-Gal3KD (c). (d) Quantification of the collagen-stained area by morphometry. (e) Type I collagen (Col1a1) gene expression analysis by qRT-PCR in the heart tissue. ; ; ; ^#, compared to the other groups.

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