Inhibition of Lysyl Oxidases Impairs Migration and Angiogenic Properties of Tumor-Associated Pericytes

Table 1

Expression of cell surface markers in pericytes derived from normal tissue and pediatric nervous system tumors.

Cell surface marker	Normal pericytes		Tumor-associated pericytes
	NP-Ad (%)	NP-Mu (%)	TP-Nbl (%)	TP-Epn (%)
CD146	95,0	65,5	0,4	46,4
NG2	99,4	94,1	22,7	99,6
PDGFRβ	93,1	70,3	63,0	59,6
CD31	0,3	0,8	1,0	10,2
CD45	0,8	0,2	0,1	0,1
CD105	5,0	11,7	2,2	7,2
CD90	34,1	60,6	24,6	99,7
CD73	100,0	100,0	100,0	100,0

Percentage of positive cells for each surface marker, within a given pericyte culture, as determined by flow cytometric analysis. NP-Ad: normal pericytes from adipose tissue; NP-Mu: normal pericytes from muscle tissue; TP-Nbl: tumoral pericytes from neuroblastoma; TP-Epn: tumoral pericytes from ependymoma.