Research Article

Overexpression of Heme Oxygenase-1 in Mesenchymal Stem Cells Augments Their Protection on Retinal Cells In Vitro and Attenuates Retinal Ischemia/Reperfusion Injury In Vivo against Oxidative Stress

Figure 2

The effects of HO-1 overexpression in MSC on intracellular ROS levels and apoptosis. MSC or MSC-HO-1 were indirectly cocultivated with RGC-5 after adding H2O2. (a) Intracellular ROS levels in RGC-5 were analyzed by flow cytometry. (b) Representative TUNEL images of RGC-5. (c) and (d) The quantitative detection of ROS levels and apoptosis of RGC-5 (). compared with control; compared with H2O2 group; compared with MSC group.
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