Clinical Study

Adipose-Derived Stromal Cells for Treatment of Patients with Chronic Ischemic Heart Disease (MyStromalCell Trial): A Randomized Placebo-Controlled Study

Table 3

(a) Computed tomography rest and stress perfusion data measured as attenuation density (AD), perfusion index (PI), and transmural perfusion ratio (TPR). (b) Left ventricle end-diastolic volume (LV EDV), LV thickness, and LV muscle mass for placebo and adipose-derived stromal cell (ASC) group.
(a)

Placebo groupASC value (differences between groups for rest values) value (differences between groups for stress values)
RestStressRestStress
BaselineFollow-up valueBaselineFollow-up valueBaselineFollow-up valueBaselineFollow-up value

AD92.9 ± 16.085.4 ± 16.00.132118.4 ± 17.8116.1 ± 15.30.58386.2 ± 14.586.0 ± 14.70.91118.7 ± 18.0117.6 ± 20.00.6750.1730.803
PI0.20 ± 0.040.23 ± 0.130.4550.35 ± 0.050.34 ± 0.090.7920.19 ± 0.040.19 ± 0.080.6120.33 ± 0.060.34 ± 0.070.280.5420.419
TPR1.15 ± 0.131.15 ± 0.130.9591.00 ± 0.061.05 ± 0.110.251.15 ± 0.071.14 ± 0.100.6551.02 ± 0.061.03 ± 0.050.7330.8280.171

Values are mean ± SD.
(b)

PlaceboASC
BaselineFollow-up valueBaselineFollow-up value value (between groups for differences)

LV EDV127.1 ± 41.9135.0 ± 41.40.203139.0 ± 40.1135.0 ± 40.10.370.126
LV thickness8.2 ± 2.48.5 ± 2.00.3277.8 ± 1.28.2 ± 1.70.1070.923
LV muscle mass151.5 ± 45.8157.4 ± 56.00.214143.1 ± 34.4139.6 ± 31.30.4490.199

Values are mean ± SD