Research Article

Predicting the Remaining Lifespan and Cultivation-Related Loss of Osteogenic Capacity of Bone Marrow Multipotential Stromal Cells Applicable across a Broad Donor Age Range

Table 1

Genes upregulated following osteogenic induction.

GeneFold upregulationSignificance
(all time points)

FRZB256.9
OMD72.4
PDGFRL55.7
LEPR29.2
IGF222.6
NGFR19.6
MSX110.4
ANGPTL48.2
MT2A7.7
SFRP17.3
TGFBR25.7
TGFBR35.7
SPP15.5
ALPL4.9
SORT14.4
DVL23.2
PDGFRA3.2
BMPER2.8
S1PR12.8
FZD12.7
CSPG42.6
FZD42.5
NGFRAP12.4
FGFR12.1
SOX90.5
NES0.4
VEGFA0.3
SFRP40.2

Only genes with significant >2-fold induction: , , , and .